Presidential elections were held in the Comoros on 21 February 2016, with a second round to be held on 18 April 2016, alongside elections for the Governors of the three islands. The presidency of the Comoros rotates between the country's three main islands; Anjouan, Grande Comore and Mohéli. The 2006 elections were limited to candidates from Anjouan and the 2010 elections to Mohélian candidates. As a result, the 2016 elections will see presidential candidacy limited to Grande Comore residents.

A primary election took place on Grande Comore on 21 February, with the three top candidates progressing to the nationwide second round on 18 April, where a plurality determines the winner.